ISSN  2587-2362  |  E-ISSN  2618-642X

Quick Search




Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province [Int J Med Biochem ]
Int J Med Biochem . Ahead of Print: IJMB-54254 | DOI: 10.14744/ijmb.2019.54254

Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province

Mustafa Sahin1, Alpaslan Karabulut2, Huseyin Kayadibi3
1Department of Medical Biochemistry, Hitit University, Erol Olcok Education and Research Hospital, Corum, Turkey
2Department of Internal Medicine, Hitit University, School of Medicine, Corum, Turkey
3Department of Medical Biochemistry, Hitit University, School of Medicine, Corum, Turkey

INTRODUCTION: To identify the incidence of thyroid dysfunction in geriatric patients in Corum province.
METHODS: Thyroid stimulating hormone (TSH), free T4 (FT4), Free T3 (FT3) tests and demographic characteristics of 220 randomized patients were retrospectively investigated. Patients with total or partial thyroidectomy surgery and those receiving any medical thyroid treatment were not included in the study. Patients were divided into five groups as subclinical hypothyroidism, hypothyroidism, euthyroid, subclinical hyperthyroidism and hyperthyroidism.
RESULTS: Of patients, 114 were male and 106 were female. The mean ages of male and female patients were 747 and 757 years. All patients had median TSH 0.94 (0.33-1.86) IU/mL, median FT4 1.14 (1.02-1.33) ng/dL, and median FT3 2.73 (2.25-3.11) pg/mL. For male patients, median TSH was 0.87 (0.36-1.66) IU/mL, median FT4 was 1.14 (1.02-1.29) ng/dL and median FT3 was 2.74 (2.18-3.15) pg/mL, while for female patients median TSH was 0.95 (0.20-2.21) IU/mL, median FT4 was 1.17 (1.06-1.38) ng/dL and median FT3 was 2.72 (2.31-3.10) pg/mL. Of males, 1.8% had subclinical hypothyroidism, 1.8% had hypothyroidism, 72.8% were euthyroid, 19.3% had subclinical hyperthyroidism and 4.4% had hyperthyroidism identified. For females, there was 2.8% subclinical hypothyroidism, 1.9% hypothyroidism, 64.2% euthyroid, 26.4% subclinical hyperthyroidism and 4.7% hyperthyroidism. When the diagnosis incidence is compared according to gender, there was no statistically significant difference observed (P=0.696).
DISCUSSION AND CONCLUSION: Independent of gender, the geriatric patient population had high incidence of subclinical hyperthyroidism which may make diagnosis of other metabolic diseases difficult or delay diagnosis. As thyroid function tests affect all metabolism, they should be investigated when assessing other metabolic diseases in the geriatric patients. We think excluding thyroid disfunctions when researching other metabolic diseases in this population of patients will gain time for accurate diagnosis and treatment. As thyroid diseases are affected by iodine amounts in geographical regions, each region should perform thyroid disease incidence studies.

Keywords: Geriatrics, hyperthyroidism, hypothyroidism



Corresponding Author: Mustafa Sahin, Trkiye
LookUs & Online Makale