A comparative study on the performances of 77 elektronika urised 2-LabUmat2 and Dirui FUS200 - H800 urine analyzers

INTRODUCTION: This study aims to compare the analytical performance of the 77Elektronika brand LabUmat2-Urised2 model integrated urine analyzer and Dirui brand FUS200-H800 model integrated urine analyzer.
METHODS: Urine samples of 139 patients randomly selected from male and female patients of all age groups who were admitted to Ufuk University Faculty of Medicine, Dr. Ridvan Ege Hospital between 24.02.2020-28.02.2020 were analyzed on both devices.
RESULTS: The results of the samples whose WBC (white blood cell), RBC (red blood cell) and Squamous epithelial were measured using two different methods in microscopic analyzers were perfectly compatible in the same range and with three parameters (Gamma values 0.916; 0.770; 0.961, respectively). For the samples where crystal and cylinder tests were carried out in microscopic analyzers, Cappa values were 0.486 and 0.495, respectively. As the result of Passing-Bablok Regression analysis used for the method comparison of microscopic analyzers, Cusum test results were p<0.01, p=0.01 and p=0.65, respectively for the linearity in the measurement of WBC, RBC and Squamous epithelial. According to the Bland-Altman Compatibility Chart prepared to determine the difference between methods, the difference between the results of the measurements of WBC, RBC and Squamous epithelial in both devices were -29.3±1.96 SD (95% CI, lower limit: -174.6; upper limit: 116); 43.3±1.96 SD (95% CI, lower limit: -119.7; upper limit: 206.2); -4.0±1.96 SD (95% CI, lower limit: -87.8%; upper limit: 79.9), respectively. When the results of the chemical analyzers of each device were compared, the findings showed that there was a high correlation between leukocyte and protein levels. When the compliance of chemical and microscopic units of each device was examined, a high correlation was found for WBC and a medium level correlation for RBC.
DISCUSSION AND CONCLUSION: Although both devices revealed similar results, confirmation with the manual microscope might be required, especially in pathological samples. Therefore, microscopic analyzers are still needed to be developed concerning method and software although automatic urine analyzers provide standardization and reduce the workload of laboratories.